Clinical Research and Clinical Trials on Down Syndrome

Clinical research is research that directly involves a particular person or group of people, or that uses materials from humans, such as their behavior or samples of their tissue.

A clinical trial is one type of clinical research that follows a pre-defined plan or protocol. By taking part in clinical trials, participants can not only play a more active role in their own healthcare, but also can access new treatments and help others by contributing to medical research.

NIH and other agencies and organizations conduct clinical research and clinical trials on a broad range of topics, including Down syndrome and health conditions related to Down syndrome.

Thinking about taking part in a clinical trial? Wondering if it's safe for your family member to get involved?

Visit the NIH Clinical Research Trials and You website. The site offers information about clinical research and clinical trials that can be helpful to people who want to get involved in clinical trials. It also provides answers to common questions about clinical research for those who aren't quite sure whether they or their family member should take part.

The National Library of Medicine, part of NIH, maintains the website as a simple way to find out about what clinical trials are ongoing, recruiting participants, and completed with results on different diseases and conditions. The site includes trials being conducted by NIH, by other government agencies and offices, and by healthcare and family organizations.

To see a list of all clinical trials on or related to Down syndrome, visit

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